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SS-Raman spectroscopy utilizes a swept-source laser, a narrow-bandwidth bandpass filter (BPF), and an extremely delicate point photoreceiver for sample recognition. These elements allow the advancement of affordable portable Raman spectrometers. Credit: Journal of Biomedical Optics (2024 ). DOI: 10.1117/ 1. JBO.29. S2.S22703
In 1928, Indian physicist Sir C. V. Raman and his associate K. S. Krishnan found that when light communicates with matter, parts of the spread light go through modifications in energy due to interaction with molecular vibrations, leading to what is referred to as Raman scattering. The discovery laid the structure for Raman spectroscopy, a strategy that makes the most of these energy modifications to produce a distinct finger print of the molecular structure of the product.
Presently, dispersive Raman spectroscopy is the go-to approach for recognizing samples in a range of fields, such as product sciences, pharmaceuticals, ecological tracking, and biomedicine. The spectrometers needed to catch and identify the spread light are large, restricting their usage outside of lab settings. Furthermore, the majority of portable Raman spectrometers have actually been established just for chemical analysis.
In a research study released in the Journal of Biomedical Opticsscientists from the Korea Advanced Institute of Science and Technology (Republic of Korea) and the Massachusetts Institute of Technology (MIT; United States) have actually established a compact swept-source Raman (SS-Raman) spectroscopy system.
The idea of SS-Raman was proposed in a previous patent however the execution has actually not been done till just recently due to the absence of narrow bandpass filters. This system is equivalent to traditional dispersive Raman spectroscopy in its capability to determine both chemical and biological products. The portable system deals with the restrictions of present portable spectrometers and opens doors for sample recognition in biomedicine.
Traditional Raman spectroscopy systems utilize a fixed-wavelength light, such as a laser, to thrill the sample and cause Raman scattering. On the other hand, SS-Raman spectroscopy utilizes a swept-source laser, which produces light over a constant series of wavelengths.
The excitation light is focused onto the sample after infiltrating a short-pass filter which gets rid of background sound. The spread light is gathered by a lens and filtered by a bandpass filter, which separates just the wanted Raman-shifted wavelength variety. The filtered light is then spotted by the extremely delicate silicon photoreceiver, which transforms the optical signal into an electrical signal for sample analysis.
“The proposed SS-Raman setup utilizes a wavelength swept-source laser (822 to 842 nm), a narrow-bandwidth bandpass filter, and an extremely delicate point photoreceiver for obtaining Raman spectra. These elements add to the advancement of compact and cost-efficient Raman spectroscopy systems,” keeps in mind Dr. Jeon Woong Kang from MIT, among the matching authors of the research study.
To examine the efficiency of the system,